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Following a single intravenous injection of adriamycin (10 mg/kg), Balb/c mice develop nephrotic proteinuria, interstitial inflammation and interstitial fibrosis (represented as % interstitial volume) and renal failure (indicated as creatinine clearance). These figures are reproduced from Wang et al [56] with copyright permission. The photomicrograph is from taken from a mouse 4 weeks after adriamycin injection (unpublished).
