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Dissociation constants (Ki) of the β-lactams used in this study
The Ki values were determined using nitrocefin as a reporter substrate.
| Inhibitor | Ki |
|---|---|
| μm | |
| Compound 1 | 83 ± 3 |
| Compound 2 | 30 ± 4 |
| Compound 3 | 404 ± 10 |
| Compound 4 | 42 ± 1 |
| Carbenicillin | 78 ± 2 |
| Imipenem | 3.2 ± 0.3 |
