FIGURE 10.

TAT-CBD3 decreases NMDA induced current in rat hippocampal neurons. A, representative traces from a single neuron, showing a control NMDA trace evoked by 50 μm NMDA (see “Experimental Procedures”), NMDA current after a 5-min perfusion of 10 μm TAT-CBD3, and NMDA current after a 10-min washout of TAT-CBD3. B, bar graph summarizing the effect of TAT-CBD3 on NMDA current of eight individual cells; four of those cells lasted long enough to finish a 10-min washout period and partially recovered from TAT-CBD3 effect. Error bars, S.E.