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Neutralization of LPS endotoxicity by Hb peptides. S. minnesota LPS was treated with 1, 10, and 100 μm concentrations of peptides. The endotoxicity of the solutions was measured using rFC-based PyroGene assay. The extent of neutralization of LPS by the peptides is plotted as a percentage of the “LPS only” control for the LPS-binding peptides (A) and non LPS-binding peptides (B). Results are the means ± S.D. of three independent experiments done in triplicate.
