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. Author manuscript; available in PMC: 2011 Oct 24.
Published in final edited form as: Hum Mol Genet. 2010 Jan 7;19(6):1119–1128. doi: 10.1093/hmg/ddp584

Figure 4.

Figure 4

Collagen type IV and blood pressure regulation. (A) Systolic blood pressure of 4-6 months old animals. (Col4a1+/Raw 99 mm Hg (n=6), WT 124 mm Hg (n=5), p<0.001 t-test) (B) Systolic blood pressure of 14 month old animals. (Col4a1+/Raw 85.1mm Hg, WT 108.1mm Hg, n=6, p< 0.001, t-test). (C) Mean arterial blood pressure of 40 day old animals (Col4a1+/Raw 70 mm Hg (n=5), WT 91 mm Hg (n=7), p<0.01, t-test). (D) Systolic blood pressure of 14 month old animals before and during treatment with L-NAME. Measurements were collected at day 0, day 7 and day 14 of treatment. (WT, n=9, Col4a1+/Raw n=7) * p< 0.05, ** p< 0.01, *** p<0.001 t- test