Table 3.

Dynamic parameters from the MOMD fits^†

Mutant	Comp.	%	τ(x) (ns)	τ(y) (ns)	τ(z) (ns)	α	β	γ
T156R1 DLPC	2	100	-	11	1.7	-23	65	-26
T156R1 DMPC	1	22	4.3	-	-	0	0	11
	2	78	-	12	2.1	-23	63	-26
T156R1 POPC	1	26	14	-	-	0	0	17
	2	74	-	20	1.7	-24	58	-18
T156R1 DiErPC	1	59	7.6	-	-	0	0	31
	2	41	17	-	2.4	-36	50	-13
T156R1/T138A	1	27	6.9	-	-	0	0	20
	2	73	-	13	2.3	-28	63	-17
T156R1/T138Q	1	49	11	-	-	0	0	22
	2	51	-	18	1.7	-34	54	-11
T156R1/T138W	1	31	4.6	-	-	0	0	13
	2	69	-	-	1.1	0	65	-31
T156R1/L168A	1	21	6.1	-	-	0	0	28
	2	79	-	13	2.7	-23	65	-27
T156R1/L168V	1	33	9.0	-	-	0	0	23
	2	67	-	13	2.4	-28	62	-22
T156R1/L168W	1	65	7.8	-	-	0	0	34
	2	35	-	-	0.96	0	55	0
T156R1/V154A	1	52	3.1	-	-	0	0	20
	2	48	-	12	3.0	-29	65	-31
T156R1/V154Q	1	64	5.4	-	-	0	39	11
	2	36	-	-	0.56	0	54	-40
T156R1/Q158A	1	39	4.6	-	-	0	0	21
	2	61	4.7	-	16	52	37	-10
T156R1/Q158N	1	50	6.2	-	-	0	0	25
	2	50	8.4	-	5.4	45	45	-2
T156R1/L160A	1	35	8.0	-	-	0	0	24
	2	65	-	13	3.2	-31	62	-19

^†The slow component is described as component 1, whereas the fast component is labeled as component 2. The slow component was fit with intermediate to slow x-axis anisotropic motion. In most cases, the majority of motional averaging in the fast spectral component was due to fast z-axis anisotropic motion. The dashes represent anisotropic correlation times from the fits that were slower than the timescale for averaging at X-band (τ > ~50 ns). In these cases, to reduce the number of parameters, the correlation times were arbitrarily set to 167 ns (R = 6.0) for the remainder of the fit and thus are not reported.