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. Author manuscript; available in PMC: 2011 Oct 24.
Published in final edited form as: Nat Genet. 2007 Apr 22;39(5):614–622. doi: 10.1038/ng2031

Table 1.

Stochastic sex chromosome LOH in F1 hybrid embryos

XmY XmXp Xm Xp Total
Dnmt3l+/− 59 61 0 0 120
Dnmt3l+/+ 57 59 2 1 119
Total 116 120 2 1 239

Genomic DNA from F1 hybrid offspring of C57BL/6 Dnmt3l+/− sires crossed with FVB/N dams was prepared at 10.5 d.p.c. The presence or absence of the Y chromosome was determined by Sry PCR, and the Dnmt3l genotype was determined by PCR (see Methods). Two polymorphic microsatellite markers (DXMit117 and DXMit1) were used to determine parental origin of the X chromosomes. The maternal (Xm) and paternal (Xp) X chromosomes are indicated.