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Decreased hippocampal activation during acquisition of contextual fear in carriers of the rs12807809 risk allele (TT, N=76) compared with rs12807809 homozygotes (TC/CC, N=36). (a) Contrast (CS+>CS− x=−24, y=−37, z=−2, k=37; t=3.54, P<0.05) is family-wise error corrected (FWE) for the region of interest (ROI). Note that colors indicate t-scores. (b) Weighted-mean scores (CS+>CS−) in the ROI separate for left (red) and right (green) hippocampus during late acquisition.
