Table 3.

SNPs with differential association (p < 0.001) with LVM among High and Low Waist Circumference (WC)"

					Overall (N = 897)			High WC (N = 495)			Low WC (N = 402)
SNP	MB	Gene	Function	Minor Allele	Beta	SE	P*	Beta	SE	P*	Beta	SE	P*	Difference in Betas	P†
rs1157480	30.264	TMTC1	flanking	A	0.004	0.014	7.88E-01	0.053	0.019	6.30E-03	-0.056	0.021	8.20E-03	0.109	1.37E-04
rs1124636	26.424	ITPR2	intron	T	-0.016	0.014	2.54E-01	0.032	0.019	9.31E-02	-0.072	0.020	2.85E-04	0.104	1.45E-04
rs9669515	30.261	TMTC1	flanking	T	0.002	0.014	8.74E-01	0.049	0.019	1.04E-02	-0.055	0.021	8.68E-03	0.104	2.31E-04
rs7970841	30.274	TMTC1	flanking	T	-0.007	0.015	6.31E-01	0.042	0.020	3.04E-02	-0.064	0.021	3.03E-03	0.106	2.46E-04
rs7963790	38.515	SLC2A13	intron	C	0.022	0.013	1.03E-01	0.064	0.017	2.40E-04	-0.030	0.019	1.20E-01	0.095	2.87E-04
rs10877703	38.561	SLC2A13	intron	A	0.012	0.013	3.37E-01	0.052	0.017	2.47E-03	-0.041	0.019	3.22E-02	0.093	2.87E-04
rs1679695	28.845	CCDC91	flanking	T	-0.044	0.022	5.20E-02	-0.106	0.028	2.12E-04	0.050	0.035	1.55E-01	0.156	5.56E-04
rs326644	32.293	BICD1	intron	C	-0.009	0.012	4.41E-01	0.024	0.016	1.34E-01	-0.059	0.018	1.23E-03	0.083	5.73E-04
rs261889	32.371	BICD1	intron	T	0.014	0.014	3.40E-01	-0.030	0.019	1.11E-01	0.066	0.021	1.65E-03	0.096	6.18E-04
rs326641	32.291	BICD1	intron	T	0.015	0.014	2.75E-01	0.059	0.018	1.23E-03	-0.032	0.020	1.06E-01	0.091	6.82E-04
rs2650128	32.352	BICD1	intron	G	0.014	0.015	3.32E-01	-0.026	0.019	1.77E-01	0.074	0.023	1.10E-03	0.100	7.10E-04
rs4356315	31.105	DDX11	flanking	G	0.014	0.012	2.38E-01	0.050	0.015	1.18E-03	-0.028	0.017	1.07E-01	0.078	7.21E-04
rs11610493	40.345	PDZRN4	flanking	G	0.014	0.013	2.57E-01	-0.023	0.017	1.70E-01	0.061	0.018	1.05E-03	0.084	7.82E-04

*adjusted for PCA1, PCA2, age, sex, hypertension, diabetes, BMI, WC, and years between LVM and risk factor measurements

† p-value calculated using a normal approximation to test for differences between the beta coefficients of high and low WC.