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. 2011 Aug 3;11:333. doi: 10.1186/1471-2407-11-333

Table 6.

Nucant pseudopeptides inhibit proliferation of human colon carcinoma cells.

Cells Nucant Number of cells % inhibition
SW480 None: Control 1,500,000 -
N7: 10 μM 1,200,000 20%
N7: 20 μM 900,000 40%
N6L: 10 μM 800,000 47%
SW620 None: Control 1,800,000 -
N7: 10 μM 1,000,000 44%
N7: 20 μM 700,000 61%
N6L: 10 μM 450,000 75%

Cells seeded in 6-well plates at 20,000 cells/ml in 2 ml culture medium were cultured in the absence (Control) or presence of N7 and N6L. Seven days after seeding, cells were trypsinized and counted. Nucant pseudopeptides were added only once 5 hours after seeding of cells. Consistently, N6L manifests at least 2-fold higher inhibitory activity compared to N7.