TABLE 2.
SELECTED POLYMORPHISMS IN CANDIDATE VITAMIN D METABOLISM GENES
| Gene | dbSNP rs# | Position* | Location | Restriction Site | Alleles |
|---|---|---|---|---|---|
| VDR | rs731236 | 46,525,024 | Ile352Ile | Taql | C>T |
| rs7975232 | 46,525,104 | Intron 8 | Apal | A>C | |
| rs2239185 | 46,530,826 | Intron 6 | - | C>T | |
| rs2107301 | 46,541,837 | Intron | - | T>C | |
| rs1540339 | 46,543,593 | Intron 3 | - | A>G | |
| rs3782905 | 46,552,434 | Intron 2 | - | G>C | |
| rs2228570 | 46,559,162 | Met1Thr | Fokl | C>T | |
| CYP24A1 | rs2296241 | 52,219,626 | Ala184Ala | - | A>G |
| rs17219315 | 52,221,853 | Intron | - | A>G | |
| rs2248137 | 52,223,150 | Intron | - | G>C | |
| rs2248359 | 52,224,925 | Locus | - | T>C | |
| CYP2R1 | rs10766197 | 14,878,456 | Unknown | - | G>A |
*
Position based on dbSNP build 129 (http://genome.ucsc.edu)
†
Frequency refers to that of the second allele listed for all samples analyzed.