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(a) The primary sequence of mature human IAPP. The peptide contains a disulfide bridge between Cys-2 and Cys-7 and has an amidated C-terminus. (b) The primary sequence of the proIAPP1–48 processing intermediate. The sequence is numbered beginning at the first residue of the intermediate. The N-terminal extension is depicted in red and the sequence of the mature hormone in black. (c) The structure of acid fuchsin. (d) The structure of fast green FCF.
