Fig. 3.

Effect of BAY on VSMC cycle progression. Histogram of propidium iodide-labeled DNA content for vehicle (Veh)- and BAY-treated cells after 24 h in the presence of 10% FBS. A trend for reduced cell numbers in G₂/M with BAY treatment is apparent (−70%; not statistically significant; p = 0.091), whereas the number of cells in the G₀/G₁ stationary phase is slightly increased. No significant effects by BAY were observed on the numbers of cells in the S phase. Data are mean ± S.E.M. of three independent experiments (each n = 6 per group).