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The presence of BAY significantly reduced (40%) PDGF-stimulated migration of VSMCs after 6 h using a transwell assay. The PKG inhibitor DT-2 completely reversed the antimigratory effects of BAY, whereas the PKA inhibitor PKI had no effect. Data are mean ± S.E.M. of three independent experiments performed in duplicate. ***, p < 0.001; **, p < 0.01; Student-Newman-Keuls method for multiple comparisons after one-way ANOVA.
