. 2011 Oct 6;51(10):2449–2454. doi: 10.1021/ci200260t

Table 1. Number of Compounds, Bioactive Templates, and Singletons within Each Category of Ion Channels in the ChEMBLfiltered Data Set.

ion channel category	total no. of compounds	total no. of templates	no. of templates selected	no. of singletons
AnionicCysLoop	1589	94	36	288
CationicCysLoop	1383	94	60	856
purinoceptors	14	2	2	3
glutamate	1586	106	59	368
Na⁺	326	30	17	63
Ca²⁺	437	46	21	108
K⁺	959	112	71	119
InwardlyRectifyingK⁺	51	9	3	13
transient receptor potential	671	42	34	51
sulfonylurea	86	13	4	11
total	7102	548	307	1880