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MRM analysis of A-T biomarker candidates. Relative protein expression levels were determined by averaging the area-under-the-Curve (AUC) for each selected MRM transition for each peptide shown in Table 4. For secretogranin-2 and IGFBP7, the fold-changes from both MRM peptides were also averaged. Statistical analysis was performed by ANOVA models using PROC MIXED in SAS. P < .05.
