Table 3.
Priority 1 and Priority 2 proteins.
| Protein name | Priority group | Swiss-Prot accession number | Peptides used for protein identification | Peptide ID confidence (%) |
Fold-Change (negative values indicate downregulation)(a) |
|---|---|---|---|---|---|
| LVRPADINFLACVMECEGKLPSLK | >99.99 | ||||
| AEEDDSLANSSDLLKELLETGDNR | >99.99 | ||||
| Proenkephalin-A | 1 | P01210 | ECSQDCATCSYR | 93.45 | 1.29 |
| ELLETGDNR | 99.31 | ||||
| ELLQLSKPELPQDGTSTLR | 99.23 | ||||
|
| |||||
| FSCFQEEAPQPHYQLR | >99.99 | ||||
| Isoform 1 of Extracellular matrix protein 1 | 1 | Q16610 | QHVVYGPWNLPQSSYSHLTR | >99.99 | 1.42 |
| NIWRDPALCCYLSPGDEQVNCFNINYLR | >99.99 | ||||
| ACPSHQPDISSGLELPFPPGVPTLDNIK | >99.99 | ||||
|
| |||||
| IESQTQEEVR | >99.99 | ||||
| TNEIVEEQYTPQSLATLESVFQELGK | >99.99 | ||||
| VLEYLNQEK | >99.99 | ||||
| Secretogranin 2 | 1 | P13521 | GQGSSEDDLQEEEQIEQAIK | >99.99 | 1.35 |
| EHLNQGSSQETDKLAPVS | >99.99 | ||||
| ALEYIENLR | 90.56 | ||||
| QYWDEDLLMK | 99.73 | ||||
|
| |||||
| Isoform 1 of CD166 antigen | 1 | Q13740 | SSPSFSSLHYQDAGNYVCETALQEVEGLK | >99.99 | 1.52 |
| ALFLETEQLK | 91.12 | ||||
|
| |||||
| ITVVDALHEIPVK | >99.99 | ||||
| SSSDTCGPCEPASCPPLPPLGCLLGETR | >99.99 | ||||
| SRYPVCGSDGTTYPSGCQLR | >99.99 | ||||
| Insulin-like growth factor binding protein 7 | 1 | Q16270 | TELLPGDRDNLAIQTR | 99.98 | −1.46 |
| EDAGEYECHASNSQGQASASAK | 99.99 | ||||
| AGAAAGGPGVSGVCVCK | >99.99 | ||||
| GTCEQGPSIVTPPK | 99.50 | ||||
|
| |||||
| YIPPCLDSELTEFPLR | >99.99 | ||||
| SPARC | 1 | P09486 | APLIPMEHCTTR | 99.96 | −1.47 |
| PPCLDSELTEFPLR | 99.52 | ||||
| RLEAGDHPVELLAR | >99.99 | ||||
|
| |||||
| GRPEAQPPPLSSEHKEPVAGDAVPGPK | >99.99 | ||||
| LADLASDLLLQYLLQGGAR | >99.99 | ||||
| ESAREEEEAEQER | >99.99 | ||||
| NSEPQDEGELFQGVDPR | >99.99 | ||||
| RPESALLGGSEAGER | >99.99 | ||||
| Neurosecretory protein VGF | 1 | O15240 | THLGEALAPLSK | >99.99 | 1.42 |
| VGEEDEEAAEAEAEAEEAER | >99.99 | ||||
| LLQQGLAQVEAGR | >99.99 | ||||
| NAPPEPVPPPR | >99.99 | ||||
| GLQEAAEER | 95.27 | ||||
| FGEGVSSPK | >99.99 | ||||
| AYQGVAAPFPK | >99.99 | ||||
|
| |||||
| TPP1 | 1 | B5MDC1 | YLTLENVADLVRPSPLTLHTVQK | 98.74 | −1.44 |
| VPIPWVSGTSASTPVFGGILSLINEHR | >99.99 | ||||
|
| |||||
| GIEDEQDLVPLEVTGVVFHYR | >99.99 | ||||
| Neurocan core protein | 1 | O14594 | RNPQELYDVYCFAR | >99.99 | 1.30 |
| ELGGEVFYVGPAR | >99.99 | ||||
|
| |||||
| HSGFEDELSEVLENQSSQAELK | >99.99 | ||||
| AEGNNQAPGEEEEEEEEATNTHPPASLPSQK | >99.99 | ||||
| GEQEHSQQKEEEEEMAVVPQGLFR | 99.07 | ||||
| ELQDLALQGAK | >99.99 | ||||
| PQALPEPMQESK | >99.99 | ||||
| Chromogranin A | 1 | P10645 | SEALAVDGAGKPGAEEAQDPEGK | >99.99 | 1.31 |
| RPEDQELESLSAIEAELEK | >99.99 | ||||
| EDSLEAGLPLQVR | >99.99 | ||||
| YPGPQAEGDSEGLSQGLVDREK | >99.99 | ||||
| SGELEQEEER | >99.99 | ||||
| TDGARPQALPEPMQESK | >99.99 | ||||
| GLSAEPGWQAK | >99.99 | ||||
|
| |||||
| AIGAVPLIQGEYMIPCEK | >99.99 | ||||
| ISVNNVLPVFDNLMQQK | >99.99 | ||||
| FDGILGMAYPR | >99.99 | ||||
| Cathepsin D | 1 | P07339 | VSTLPAITLK | 98.91 | −1.37 |
| TMSEVGGSVEDLIAK | >99.99 | ||||
| VGFAEAAR | 90.97 | ||||
| LLDIACWIHHK | 99.98 | ||||
|
| |||||
| VTEIWQEVMQR | >99.99 | ||||
| LACCVVGVCGPGLWER | >99.99 | ||||
| SOD3 | 1 | P08294 | AGLAASLAGPHSIVGR | 96.66 | −1.37 |
| AVVVHAGEDDLGR | >99.99 | ||||
| RDDDGALHAACQVQPSATLDAAQPR | >99.99 | ||||
| GGNQASVENGNAGR | >99.99 | ||||
|
| |||||
| NGVNVISGPIFDYDYDGLHDTEDKIK | 99.71 | ||||
| YDAFLVTNMVPMYPAFK | >99.99 | ||||
| SYTSCCHDFDELCLK | >99.99 | ||||
| NKLDELNKR | >99.99 | ||||
| RLHYANNR | >99.99 | ||||
| VNSMQTVFVGYGPTFK | >99.99 | ||||
| DIEHLTSLDFFR | >99.99 | ||||
| ENPP2 | 1 | Q13822 | EIDKIVGQLMDGLK | >99.99 | −1.36 |
| TEFLSNYLTNVDDITLVPGTLGR | >99.99 | ||||
| RWHVAR | 92.27 | ||||
| SCGTHSPYMRPVYPTK | >99.99 | ||||
| SYPEILTLK | 94.45 | ||||
| QAEVSSVPDHLTSCVRPDVR | 99.79 | ||||
| GESHWVDDDCEEIK | >99.99 | ||||
| VMPNIEK | 94.62 | ||||
| IEDIHLLVER | >99.99 | ||||
| VSPSFSQNCLAYK | 99.85 | ||||
| KPDQHFKPYLK | 99.79 | ||||
| PAVLYR | 91.70 | ||||
| PAGFVRPPLIIFSVDGFR | >99.99 | ||||
| CFFQGDHGFDNK | 90.16 | ||||
| QMSYGFLFPPYLSSSPEAK | 99.03 | ||||
|
| |||||
| Insulin-like growth factor binding protein complex acid abile chain | 2 | P35858 | LAYLQPALFSGLAELR | >99.99 | −1.45 |
|
| |||||
| Caspase recruitment domain-containing protein 14 | 2 | Q9BXL6 | GALPGAK | 95.91 | −1.95 |
|
| |||||
| Endothelial cell-selective adhesion molecule | 2 | Q96AP7 | QLPSFQTFFAPALDVIR | 99.94 | 1.95 |
|
| |||||
| Isoform 1 of phosphatidylinositol 3-kinase regulatory subunit gamma | 2 | Q92569 | LGEIHDSK | 90.36 | −2.16 |
|
| |||||
| Neutral amino acid transporter B | 2 | Q15758 | SCTVLNVEGDALGAGLLQNYVDR | 90.14 | −1.87 |
|
| |||||
| Isoform 1 of latrophilin-1 | 2 | O94910 | TDDKICDADPFQMENVQCYLPDAFK | >99.99 | 1.57 |
|
| |||||
| Isoform 1 of histone-lysine N-methyltransferase MLL3 | 2 | Q8NEZ4 | IQPPIAQLPIK | 91.36 | 2.03 |
(a)The fold-changes are the average values from all the peptides used for protein quantification; individual values from individual peptide are given in the supplementary data.