Figure 5.
Early loss of Gli2 function results in the reduction of corticotropes and lactotropes at E17.5. (A-J) Immunostaining of different pituitary cell type markers. (K) Quantification of different pituitary cell types in WT and FoxG1Cre;Gli2 mutants (* denotes P<0.05, ** denotes P<0.01, n=6 embryos). (L) FoxG1Cre;Gli2 mutants did not grow as well as WT pups after birth. Seven pups from four litters were tracked for each genotype. The number on each dot indicates surviving pups at that time. Scale bars: 100 μm.