Figure 2. DEF201 prophylaxis limits liver disease and viral loads in PICV-infected hamsters.

Animals were treated as described in Figure 1 and sacrificed on day 7 of infection for analysis of serum (A) ALT and (B) virus titer, and (C) liver and (D) spleen viral titers. *P<0.05, **P<0.01, compared to placebo-treated animals. ^a P<0.05, ^b P<0.01, compared to rAd EV-treated animals.