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. 2011 Oct 24;6(10):e26615. doi: 10.1371/journal.pone.0026615

Figure 6. Phenethyl isothiocyanate (PEITC)-mediated inhibition of prostate cancer cell migration is augmented by a γ-secretase inhibitor.

Figure 6

Representative images (Boyden chamber assay) depicting migration of (A) LNCaP and (C) PC-3 cells after 24-hour treatment with dimethyl sulfoxide (DMSO) or 5 µM PEITC in the absence or presence of 50 µM DAPT at 200× magnification. Quantitation of migrated (B) LNCaP cells and (D) PC-3 cells after 24-hour treatment with DMSO or 5 µM PEITC and/or 50 µM DAPT. Three to four fields on each filter were scored for migrated cells under an inverted microscope. Results shown are mean ± SD (n = 3). *Significantly different (P<0.05) between the indicated groups by one-way ANOVA followed by Bonferroni's multiple comparison test. Each experiment was repeated twice, and representative data from one such experiment are shown.