Figure 3.

IB2−/− mice are less socially interactive. Pairs of IB2+/+ or IB2−/− male (A, B) or female (C, D) mice (mixed background) were placed in a large new cage and monitored over 10 min for social interaction, judged as close pursuit or physical contact with sniffing. IB2−/− pairs engaged in significantly less total interaction time (A, C), which for males was attributed to shorter duration of interaction per contact (B). Behaviors are illustrated in supplemental Movie 1 (available at www.jneurosci.org as supplemental material).