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. 2010 Nov 3;30(44):14805–14816. doi: 10.1523/JNEUROSCI.1161-10.2010

Figure 5.

Figure 5.

Ultrastructurally and molecularly normal synapses in IB2−/− mice. A–D, Electron micrographs of synapses in cerebellar granule layers (A, B) and molecular layers (C, D) of IB2+/+ (A, C) and IB2−/− (B, D) animals. Synapses (arrows) in IB2−/−cerebellum appear normal. gl, Glomerulus; d, dendritic spine; pft, parallel fiber terminal; ds, Purkinje dendritic spine. Scale bar, 500 nm. E, F, Immunoblot detection of glutamate receptor subunit enrichment in cerebral cortical synaptosome-derived (E) and cerebellar glomerulus-derived (F) PSD preparations. Receptor abundances in IB2−/− PSDs are normal.