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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Trends Neurosci. 2011 Sep 30;34(11):599–609. doi: 10.1016/j.tins.2011.08.005

Figure 1.

Figure 1

Resolvins and their routes of formation. (a) Omega-3 polyunsaturated fatty acids include DHA and EPA, and are derived from dietary essentially fat (especially enriched in fish). RvD1 and AT-RvD1 are derived from DHA, whereas RvE1 is derived from EPA. Distinct synthetic enzymes, including COX-2, cytochrome P450, and 5- and 15-lipoxygenase are involved in these processes. See Ref [49] for detailed review on the biosynthesis of resolvins. (b) Chemical structures of the resolvins that are discussed in this review.