Table 1.

Anti-inflammatory actions of resolvins in animal models of inflammation

Resolvins	Animals	Inflammatory conditions	Anti-inflammatory effects	Refs
RvE1	Mouse	Dorsal air pouch	Stop neutrophil recruitment	[42]
		Peritonitis	Reduce neutrophil recruitment	[48,59]
			Regulate cytokine and chemokine expression	[48,59]
		Retinopathy	Alleviate neovascularization and reduce TNF-a expression	[61]
		Colitis	Decrease neutrophil recruitment and improve survival	[62]
		Allergy	Resolve allergic airway inflammation	[63, 64]
			Regulate NK cell migration	[63, 64]
		Ocular Lesion	Control HSV-induced ocular inflammatory lesions	[65]
			Increase IL-10 and decrease IL-6 expression	[65]
		Lung injury	Protect bacterial pneumonia and acute lung injury	[66]
			Enhance clearance of bacteria	[66]
RvD1	Mouse	Kidney ischemia	Protect from ischemia-reperfusion-induced kidney damage	[67]
			Regulate macrophage function	[67]
		Peritonitis	Stop neutrophil recruitment and modulate miRNAs	[68]
		Dorsal skin air pouch	Stop neutrophil recruitment	[46]
		Oxidative stress	Control inflammation during oxidative stress	[69]
AT-RvD1	Mouse	TMJ inflammation	Protect inflammation in the TMJ	[70]