Table 2.
Descriptive statistics; numbers and crude incidence rates stratified by attained age, time period of follow-up, smoking status and educational level at baseline. Age-adjusted hazard ratios given for smoking status and educational level.
| Outcome: Parkinson’s disease
|
Outcome: Parkinsonian disorders
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| IR/100,000 | IR/100,000 | ||||||||
| N | PYR | N | PYR | ||||||
| Study population | |||||||||
| (n=20 226) | 293 | 49.8 | 336 | 57.1 | |||||
| Attained age | <49 | 2 | 1.1 | 4 | 2.2 | ||||
| 50–64 | 30 | 13.0 | 36 | 15.6 | |||||
| 65–79 | 167 | 113.0 | 193 | 131.0 | |||||
| >80 | 94 | 315.0 | 103 | 346.0 | |||||
| Time period | 1967–1979 | 48 | 26.3 | 56 | 30.7 | ||||
| 1980–1989 | 87 | 53.1 | 94 | 57.3 | |||||
| 1990–1999 | 82 | 61.1 | 95 | 70.7 | |||||
| 2000–2009 | 74 | 79.1 | 89 | 95.1 | |||||
| HR | 95% CI | HR | 95% CI | ||||||
|
|
|
||||||||
| Smoking statusa | Never smoker | 149 | 84.1 | 1 | ref | 170 | 96.0 | 1 | ref |
| Current smoker | 78 | 37.6 | 0.51 | 0.39 – 0.68 | 90 | 43.4 | 0.52 | 0.40 – 0.67 | |
| Past smoker | 50 | 42.8 | 0.74 | 0.54 – 1.02 | 56 | 47.9 | 0.72 | 0.53 – 0.97 | |
| Educational level | Only compulsory | 135 | 54.2 | 1 | ref | 155 | 62.3 | 1 | Ref |
| Above compulsory | 101 | 43.6 | 1.12 | 0.86 – 1.44 | 117 | 50.5 | 1.12 | 0.88 – 1.42 | |
a
Smoking status in 1961 or 1963 for the men born 1886–1925 and in 1973 for the men born 1926–1947 (baseline).
IR = Incidence rate, PYR = Person-years, HR = Hazard ratio, CI = confidence interval.