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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Exp Gerontol. 2011 Aug 7;46(11):905–914. doi: 10.1016/j.exger.2011.08.001

Fig. 3.

Fig. 3

ABR threshold shifts in C57BL/6J mice treated with a selective ADK inhibitor ABT-702 or control vehicle solution for 6 months (early treatment). (A) ABR threshold shifts for auditory clicks and tone pips (4–28 kHz) were calculated as the difference between ABR thresholds at 9 months and baseline ABR thresholds at 3 months. (B–G) ABR threshold shifts at monthly intervals (4–9 months) relative to baseline ABR thresholds measured at 3 months. Data are expressed as means ± SEM (n = 8). *P = 0.045 (10 kHz); *P = 0.034 (16 kHz).