Figure 3.
(a) Fluorescence microscopy images of HeLa cells incubated with aptamer nano-flares and control particles for 2 hrs. The red channel is Cy5 fluorescence associated with activated aptamer nano-flares, the green channel is fluorescence associated taxol-Alexa 488 and specific for tubulin, and the blue channel is fluorescence associated with Hoechst 3342 and specific for the nucleus. Scale bar is 20μm. (b) Cell-associated fluorescence (Cy5) of populations treated with aptamer nano-flares and control particles as determined by flow cytometry. Inset numbers indicate the mean fluorescence value of the population.
