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IC50 of PTX-DNA@AuNPs 3, Paclitaxel and compound 1 after 12 and 48 h incubation in MCF7, SKOV-3 and MES-SA/Dx5 cells.
| Incubation time (h) | IC50 (nM Paclitaxel) | |||
|---|---|---|---|---|
| PTX-DNA @AuNPs 3 |
Paclitaxel | Compound1 | ||
| MCF7 | 12 | 119.4 | >1000 | >1000 |
| 48 | 52.6 | 193.0 | 133.2 | |
| SKOV-3 | 12 | 4.3 | 175.6 | >1000 |
| 48 | 17.5 | 28.9 | 188.0 | |
| MES-SA/Dx5 | 12 | 118.0 | >1000 | >1000 |
| 48 | 104.5 | >1000 | >1000 | |
