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. 2011 Oct 17;7:1421–1435. doi: 10.3762/bjoc.7.166

Table 5.

Effect of the fluorinating agent on the catalytic fluorination of F1 with 10 mol % K1.

graphic file with name Beilstein_J_Org_Chem-07-1421-i005.jpg

Entry Reagent Time Conversion (%) ee (%)

1 F–TEDAa <5 h >90 28
2 NFTh <30 h >90 32.5
3 NFSI 5 d 90 28.0
4 NFPy 5 d 30 28.8
5 NFColl 5 d <5
6 F2-bipy 7 weeks 80 ≤3
7 p-TsN(F)Me >1 week 0
8 SaSu–NF >1 week 0

a5 mol % of catalyst.