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. 2011 Feb;59(2):146–157. doi: 10.1369/jhc.2010.956607

Figure 3.

Figure 3.

Correlation of formalin-fixed paraffin-embedded (FFPE) biopsy microarray data with protein expression. ER RNA expression is measured by probe set 205225_at and HER2 RNA expression by probe set. ER and HER2 protein status is determined by immunohistochemistry and SISH. (A) Differential ER RNA expression between ER+ and ER− biopsies. (B) Receiver operating characteristic (ROC) curve showing a strong separation between ER+ and ER− biopsies. (C) Differential HER2 RNA expression between HER2+ and HER2− biopsies. (D) ROC curve showing a strong separation between HER2+ and HER2− biopsies.