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Arylsulfatase B (ARSB) activity and immunohistochemistry in paired samples of normal and malignant human colonic tissue. (A) Immunohistochemistry demonstrates prominent ARSB staining in the membranes, nuclei, and cytoplasm of the normal tissue. (B) In contrast, ARSB immunostaining in the tumor is markedly reduced. ARSB immunostaining is brown; no counterstain is present. Scale bar is 100 µm.
