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. 2011 Mar;59(3):278–288. doi: 10.1369/0022155410397999

Figure 6.

Figure 6.

α–Melanocyte-stimulating hormone (α-MSH) localization in human uninjured skin, early burn wounds, and hypertrophic scars. α-MSH immunostaining was absent in uninjured skin (A, E). In contrast, α-MSH immunostaining was robust throughout the epidermis in an early burn wound (<1 month postinjury), (B) a hypertrophic scar 10 months after injury (C), and a hypertrophic scar 2 years postinjury (D). α-MSH immunostaining was also robust in the dermis after cutaneous injury and was localized to dermal fibroblasts in an early burn wound (<1 month post-injury) (F), a hypertrophic scar 10 months after injury (G), and a hypertrophic scar 2 years postinjury (H). Magnification bar = 50 µm.