Table 1.
Expression of Focal Adhesion Proteins in Developing and Adult Rat Kidneys
FAK | Paxillin | ILK | Hic-5 | |
---|---|---|---|---|
E13–E15 |
||||
Blastema | ± | ± | + | + |
Ureteric bud | ++ | ++ | + | − |
Mesenchymal cells | + | + | + | + |
E16–E18 |
||||
Vesicles | + | + | + | ± |
Comma-, S-shaped bodies | ++ | ++ | ++ | + |
Gl epithelial cells | ± | + | + | + |
Gl endothelial cells | ++ | ++ | ++ | ++ |
Mesangial cells | ++ | ++ | ++ | ++ |
Ureteric bud branches | ++ | ++ | + | − |
Mesenchymal cells | + | ± | + | + |
P1–P7 |
||||
Vesicles | + | + | + | ± |
Comma-, S-shaped bodies | + | + | + | ± |
Gl epithelial cells | ± | + | + | − |
Gl endothelial cells | + | + | ++ | ++ |
Mesangial cells | + | + | ++ | + |
Tubular cells | + | + | ± | − |
Collecting duct cells | + | ± | + | − |
Mesenchymal cells | + | ± | + | + |
P20–P42 |
||||
Gl visceral epithelial cells | − | − | ++ | − |
Gl parietal epithelial cells | ± | − | ± | − |
Gl endothelial cells | − | − | + | − |
Mesangial cells | − | − | ± | − |
Proximal tubular cells | + | − | ++ | − |
Distal tubular cells | − | + | + | − |
Collecting duct cells | ± | ± | + | − |
Interstitial cells | − | − | − | VSMC |
Note: – = negative staining; ± = faint staining; + = mild staining; ++ = strong staining; Gl = glomerular; VSMC = vascular smooth muscle cells.