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. 2011 Oct;13(10):961–970. doi: 10.1593/neo.11828

Figure 3.

Figure 3

REV3 depletion changes cell cycle distribution of cancer cell lines. Cells were mock treated or transduced with lentiviral-based particles containing either shSCR or shREV3 and/or lentiviral-based particles containing shP53. After 1 week, cell cycle distribution was measured by BrdU/propidium iodide staining and subsequent FACS analysis. The averages of three independent experiments are given for A549, A549 shP53, p53-proficient HCT116, and p53-deficient HCT116 cells, whereas representative experiments are shown for SDM104 and AD293 cells. *P < .05. **P < .01. Shown are means ± SD.