Table 2: Comparison of Health related quality of life “SF36 subscales” between adolescents with sickle cell disease (SCD) and the comparison group.

	Adolescents with SCD (N=180)		Adolescents without SCD (N=202)
SF-36 subscales	Mean ± SD	Alphaa	Mean ± SD	Alpha	Effect size Cohen’s d	P value
Physical functioning	58.34±20.76	0.849	80.25±23.45	0.901	0.988	0.001
Role physical	23.10±33.70	0.852	76.36±33.85	0.801	-1.570	0.001
Role emotional	43.04±41.43	0.870	51.32±41.27	0.803	-0.200	0.051
Bodily pain	33.74±27.23	0.731	81.26±20.30	0.783	-1.978	0.001
Vitality	46.51±18.03	0.714	54.73±17.60	0.812	-0.461	0.001
General health	37.58±22.04	0.694	66.81±14.65	0.781	-1.562	0.001
Emotional well-being	53.89±18.32	0.740	61.19±18.32	0.801	-0.398	0.001
Social functioning	44.73±24.75	0.710	62.31±20.77	0.721	-0.769	0.001

SD=Standard Deviation, ^aChronbach’s alpha correlation coefficient