Table 3. Cumulative Toxicity seen in All Patients (n=23).
| AE Category | CTCAE v3.0 Grade | ||||||
|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | Total | |
| Allergy/Immunology | 17 | 4 | 0 | 1 | 1 | 0 | 23 |
| Bone Marrow | |||||||
| Anemia | 0 | 6 | 13 | 4 | 0 | 0 | 23 |
| Leukopenia | 4 | 6 | 9 | 2 | 2 | 0 | |
| Neutropenia | 7 | 0 | 7 | 5 | 4 | 0 | |
| Thrombocytopenia | 13 | 8 | 2 | 0 | 0 | 0 | |
| Other | 20 | 0 | 2 | 1 | 0 | 0 | |
| Auditory/Ear | 19 | 0 | 4 | 0 | 0 | 0 | 23 |
| Cardiac | 21 | 1 | 0 | 1 | 0 | 0 | 23 |
| Constitutional | 5 | 12 | 4 | 2 | 0 | 0 | 23 |
| Dermatologic | 4 | 4 | 15 | 0 | 0 | 0 | 23 |
| Gastrointestinal | |||||||
| Nausea | 4 | 14 | 3 | 2 | 0 | 0 | 23 |
| Vomiting | 9 | 9 | 3 | 2 | 0 | 0 | |
| Other | 2 | 12 | 8 | 0 | 1 | 0 | |
| Hemorrhage | 22 | 1 | 0 | 0 | 0 | 0 | 23 |
| Infection | 16 | 0 | 4 | 3 | 0 | 0 | 23 |
| Lymphatic | 22 | 1 | 0 | 0 | 0 | 0 | 23 |
| Metabolic | 6 | 6 | 6 | 5 | 0 | 0 | 23 |
| Neurologic | |||||||
| Neurosensory | 9 | 12 | 1 | 1 | 0 | 0 | 23 |
| Other | 17 | 5 | 1 | 0 | 0 | 0 | |
| Ocular/Visual | 20 | 3 | 0 | 0 | 0 | 0 | 23 |
| Pain | 5 | 12 | 5 | 1 | 0 | 0 | 23 |
| Pulmonary | 19 | 3 | 1 | 0 | 0 | 0 | 23 |
Abbreviation: CTCAE v.3.0: National Cancer Institute Common Toxicity Criteria for Adverse Events, Version 3.0