Table 1.

Host transcription factors that bind the JC virus promoter and affect viral replication

Protein	Activity for JC virus	Activity
		Glial	Lymphoid	Stromal tonsil
AP-1	Activator/repressor	+	−	+
C/EBPβ	Repressor	+	−	−
DDX1	Activator	+	−	−
Egr-1	Activator	+	−	−
GF-1/Sμpb-2	Activator	+	−	−
HIF-1α	Activator	+	−	−
LCP-1	Activator	+	−	−
NFAT4	Activator	+	−	−
NFκB	Activator	+	−	−
NF-1A	Repressor	+	−	−
NF-1X	Activator	+	+	+
Oct-6/tst-1/SCIP	Activator	+	−	−
Purα	Activator/repressor	+	−	−
Spi-B	N.D.	+	+	−
Sp1	Activator	+	−	−
YB-1	Activator	+	−	−

N.D. not determined for JC virus infection, - activity not determined in this cell type