Table 2.

Measurement precision for volumes (cm³) in healthy control subjects and subjects with DM-PN with pooled rater results.

	Bone*
	Cal	Cub	Cun1	Cun2	Cun3	Met1	Met2	Met3	Met4	Met5	Nav	Tal
Healthy Controls
Both Feet Combined
Mean Volume	67.4	12.4	9.6	3.8	5.4	15.2	7.7	6.3	6.3	7.2	10.3	35.5
RMS-SD† (LSC)**	0.10 (0.27)	0.03 (0.09)	0.03 (0.08)	0.03 (0.09)	0.02 (0.06)	0.06 (0.16)	0.04 (0.12)	0.03 (0.07)	0.02(0.06)	0.03 (0.08)	0.03 (0.08)	0.09 (0.25)
RMS-%CV§ (%LSC)#	0.1 (0.4)	0.3 (0.7)	0.3 (0.9)	0.9 (2.5)	0.4 (1.2)	0.4(1.0)	0.5 (1.5)	0.5 (1.3)	0.4 (1.0)	0.4 (1.2)	0.3 (0.9)	0.3 (0.7)
DM-PN Group
Both Feet Combined
Mean Volume	64.4	12.4	9.3	3.8	5.2	15.1	7.7	6.9	6.9	7.5	10.6	34.0
RMS-SD (LSC)	0.23 (0.64)	0.06 (0.16)	0.04 (0.12)	0.03 (0.08)	0.03 (0.08)	0.05 (0.15)	0.04 (0.12)	0.03 (0.09)	0.05(0.14)	0.03 (0.09)	0.05 (0.13)	0.10(0.27)
RMS-%CV (%LSC)	0.3 (0.9)	0.4 (1.2)	0.4 (1.2)	0.7 (2.0)	0.5 (1.5)	0.3(0.8)	0.5 (1.5)	0.5 (1.3)	0.6 (1.7)	0.4 (1.1)	0.4 (1.2)	0.3 (0.7)

^*Cal = calcaneus, Cub = cuboid, Cun1 = cuneiform 1, Cun2 = cuneiform 2, Cun3 = cuneiform 3, Met1 = metatarsal 1, Met2 = metatarsal 2, Met3 = metatarsal 3, Met4 = metatarsal 4, Met5 = metatarsal 5, Nav = navicular, Tal = talus;

^†root-mean-square standard deviation;

^§root-mean-square percent coefficient of variation;

^**Least significant change; ** Values calculated from Equation 1;

^#Values calculated from Equation 2.