. Author manuscript; available in PMC: 2012 Jun 1.

Published in final edited form as: Magn Reson Med. 2011 Jan 19;65(6):1759–1767. doi: 10.1002/mrm.22762

Table 3.

Association between ADC and DCE-MRI kinetic parameters for 100 lesions.

	n (%)	ADC (×10^-3 mm²/s) (Mean ± SD)	Association with ADC (p-value)

Peak Initial Enhancement (%)			0.182^*
50-99	9 (9%)	1.60 ± 0.58
100-199	74 (74%)	1.57 ± 0.43
>200	17 (17%)	1.77 ± 0.38

Predominant Curve Type			0.052^**
Persistent	88 (88%)	1.64 ± 0.44
Plateau	5 (5%)	1.48 ± 0.12
Washout	7 (7%)	1.32 ± 0.38

Worst Curve Type			0.310^**
Persistent	18 (18%)	1.78 ± 0.47
Plateau	31 (31%)	1.60 ± 0.41
Washout	51 (51%)	1.55 ± 0.43

P-value from generalized estimating equations (GEE) with “independence” correlation structure, analogous to Student’s t test with sandwich standard errors to adjust for multiple lesions in some patients.

^**

P-value represents global factor effect, determined by score statistics for type 3 GEE analysis.