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. 2011 Jul 8;39(19):8457–8471. doi: 10.1093/nar/gkr451

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Schematic representation of base pairing between the preCore positions analyzed, which correspond to the stem–loop structure. The columns in the center indicate the consensus sequence obtained from the laboratory’s entire collection of genotypes A sequences (bold characters). The ‘Nucleotide changes’ column indicates the percentage of each nucleotide change (%A, %C, %T and %C) and the total changes (%Tot) for all positions, attending to the master sequence. The ‘Amino acid (AA) changes’ column indicates the codon representing the position (N), the amino acid coded from the master sequence (WT), and the percentage of sequences that code for a different amino acid (%MT).