Table 1.
Baseline biochemical and serological markers, and treatment characteristics of the seven patients included in the study
ID | Baseline |
Lamivudine treatment |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
HBV DNA (IU/ml) | HBeAg | ALT (IU/ml) | HBV genotype | Type response | Months | HBV DNA (IU/ml) | ALT (IU/ml) | Type mutation | Rescue treatment | |
1 | >108 | N | 392 | D | VBK | 48 | 3.6 × 105 | 31 | M204V | LAM+ADV |
2 | 6.6 × 106 | N | 167 | A2 | SVR | 24 | <20 | 30 | – | – |
3 | 1.2 × 106 | N | 54 | A2 | SVR | 24 | <20 | 33 | – | – |
4 | >108 | P | 52 | D | VBK | 12 | 6.2 × 106 | 281 | M204IV | LAM+TDF |
5 | 3.3 × 106 | N | 78 | A2 | VBK | 34 | 8.3 × 104 | 401 | M204MIV | LAM+ETV |
6 | >108 | P | 214 | A2 | VBK | 24 | 1.3 × 107 | 93 | M204V | LAM+TDF |
7 | 2 × 106 | N | 117 | D | VBK | 12 | 2.2 × 104 | 103 | L180LM | LAM+ADV |
SVR, sustained virologic response.