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. 2011 Jul 6;39(19):8531–8543. doi: 10.1093/nar/gkr530

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — (A) Schematic of U12 snRNA showing the sequence and predicted secondary structure of WT SLIII-THL. Mutations (1–6) made in the SLIII-THL region of U12 snRNA are illustrated. (B) Splicing phenotypes of P120 branch site UC84/85AG mutant co-expressed with the indicated SLIII-THL mutants of U12 snRNA. Lane numbers 1 through 6 correspond to mutants 1 through 6 shown in (A). (C) Quantitative analysis of spliced/unspliced phenotypes from the gel image shown in (B). (Compl., complementary; Rev Compl., reverse complementary).