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. 2011 Oct 25;5(10):e1364. doi: 10.1371/journal.pntd.0001364

Figure 2. Changes of images and serum antibody levels against rAgB in CE cases during albendazole therapy.

Figure 2

1. Patients with regular treatment. (A): Hepatic CE2 was cured after 18 months treatment (A-1: at diagnosis; A-2: 12 months; A-3: 18 months). (B): Hepatic CE1 was cured following 30 months treatment (B-1: at diagnosis; B-2: 6 months; B-3: 30 months). (C): CE2 was improved in abdominal cavity following 42 months treatment (C-1: at diagnosis; C-2: 36 months; C-3: 42 months). (D): Hepatic CE1 was aggravated following 30 months treatment (D-1: at diagnosis; D-2: 6 months; D-3: 30 months). 2. Patients with poor compliance of treatment. (E): Hepatic CE (E-1: CL type cyst at diagnosis; E-2: CE3 type cyst with daughter cyst at 30 months). (F): Hepatic CE (F-1: CE1 type cyst at diagnosis; F-2: unchanged cyst at 12 months). (G): Hepatic CE (G-1: CE1 type cyst at diagnosis; G-2: the unchanged cyst at 6 months). (H): Hepatic CE (H-1: CE3 type cyst at diagnosis; H-2: CE2 type cyst at 12 month). Patient E and G refused to donate blood samples when followed up. 3. ELISA OD values in 13 CE1 cases before and after treatment (3 months to 18 months). 4. In seven CE1 cases (P1-P7) with seronegative response at diagnosis, six (P1-P6) converted to be seropositive following 3 months to 18 months treatment. Concurrently the cyst changed to CE3a from CE1 type in all these six cases. 5. In two albendazole-cured CE1 cases, specific antibody levels were initially elevated and subsequently declined during treatment, but remained positive when CE was cure. 6. In two albendazole-cured or improved CE2 patients, (A): stability of specific antibody levels in a cured CE2 case; (B): initial elevation followed by subsequent decline of specific antibody levels in an improved CE2 patient. The arrow referred to the time when CE was found to be cured.