Table 5. Genes with top-scoring antiviral and proviral expression profiles.

Gene name	Profile score	infected vs. uninfected
trophoblast glycoprotein	−5	n n n
GalNAc-T7	−4	+ + +
sperm associated antigen 1	−4	+ + +
tubulin, alpha 1a	−4	n + +
neutral cholesterol ester hydrolase 1	−4	n + +
interleukin 17D	−4	n n –
proline-serine-threonine phosphatase interacting protein 2	−4	n + n
discoidin domain receptor tyrosine kinase 1	−4	n n +
lectin, galactoside-binding, soluble, 1	−4	n n +
ependymin related protein 1	−4	n n n
MHC class I polypeptide-related sequence B	−4	n n n
TIMP metallopeptidase inhibitor 1	−4	n n n
complement component 3	5	n – n
peptidoglycan recognition protein 2	4	– – –
potassium channel, subfamily T, member 2	4	– – –
coagulation factor XII (Hageman factor)	4	n – –
annexin A9	4	n – –
orosomucoid 2	4	n – –
complexin 1	4	n – –
hydroxysteroid (11-beta) dehydrogenase 2	4	n – –
transmembrane protein 86B	4	n – –
solute carrier family 7, member 10	4	n – –
haptoglobin	4	n – –
serpin peptidase inhibitor, clade C (antithrombin), member 1	4	n – –
haptoglobin-related protein	4	n – –
left-right determination factor 1	4	n – n
reelin	4	+ n n
argininosuccinate synthetase 1	4	n – n
ATP-binding cassette, sub-family B (MDR/TAP), member 4	4	n n n
KIAA1462	4	n n n
orosomucoid 1	4	n n n
coagulation factor V (proaccelerin, labile factor)	4	n n n

Genes with a profile score of <3 (antiviral profile) are listed above and >3 (proviral profile) are listed below the line. Also, given is the change in regulation of the gene in Huh-7, Huh-7.5.1 and Huh-7.5.1c2 cells (in that order) from uninfected versus infected comparisons, where “n” represents no significant differential expression, “+” represents upregulation in the infected cell and “–” represents downregulation in the infected cell.