Table 3. Differences in kinetic parameters for Ca2+ signals evoked by different agonists.
Cerebellar astrocytes | Cortical astrocytes | ||||||||
Condition | Rise | AUC | Peak | Lat | Condition | Rise | AUC | Peak | Lat |
Glu vs ATP | 0.45 | 0.28 | 0.26 | 0.32 | Glu vs ATP | 0.15 | 0.23 | 0.037 | 0.27 |
His vs ATP | 0.23 | 0.27 | 0.19 | 0.53 | His vs ATP | 0.40 | 0.16 | 0.11 | 0.46 |
Glu vs His | 0.46 | 0.24 | 0.28 | 0.41 | Glu vs His | 0.26 | 0.13 | 0.10 | 0.38 |
Three agonists: ATP, glutamate (glu) and histamine (his) were compared at a concentration of 1 mM. Values of difference (D) were calculated as outlined in Methods. Lower values indicate a greater degree of similarity between the distributions.