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. Author manuscript; available in PMC: 2011 Oct 25.
Published in final edited form as: J Med Chem. 2011 Jan 25;54(5):1421–1429. doi: 10.1021/jm101443u

Figure 8.

Figure 8

(a) Stereoview of the van der Waals surface (blue) of the PYR binding site in DHFR. Waters and NADPH molecule bound at the active site have been removed for clarity. Coordinates for DHFR are from PDB code 2BL9.14 (b) Stereoview of the van der Waals surface (green) of the PYR binding site of HexB.