Table 1.

Demographic and clinical characteristics of participants in a study of monoamine oxidase A inhibitor occupancy during treatment for major depressive episodes

	Group, no.*†
Characteristic	Moclobemide, n = 6	St. John’s wort, n = 7	Control, n = 10
Age, mean (SD) yr	32 (8)	36 (8)	29 (11)
Women	4	4	5
Men	2	3	5
Major depressive episode
1st	0	2	0
2nd	2	2	0
3rd	2	1	0
> 3	2	2	0
Previous antidepressant treatment‡	6	3	0

SD = standard deviation.

^*Unless otherwise indicated.

^†Six participants in the control group, 1 patient in the moclobemide group and 3 patients in the St. John’s wort group underwent the protocol on the HRRT PET scanner. Four participants in the control group, 5 patients in the moclobemide group and 4 patients in the St. John’s wort group underwent the protocol on the GEMS 2048–15B PET scanner.

^‡In the moclobemide group, 1 study participant was free of medication for > 5 weeks, a second for > 8 weeks, all others for > 5 months. In the St. John’s wort group, all participants were free of medication for > 1 year.