Table 3.
Product type | Women years | Anticoagulation (confirmed) | Not recorded | ||||
---|---|---|---|---|---|---|---|
No of events* | Adjusted relative risk† (95% CI) | No of events* | Adjusted relative risk† (95% CI) | % confirmed | |||
Non-use | 4 960 730 | 1004 | 1 (reference) | 808 | 1 (reference) | 55.4 | |
Progestogen with 50 µg ethinylestradiol: | |||||||
Norethisterone | 6848 | 7 | 6.24 (2.95 to 13.2) | 4 | 5.10 (1.90 to 13.7) | 63.6 | |
Levonorgestrel | 23 691 | 22 | 4.49 (2.94 to 6.85) | 9 | 2.34 (1.21 to 4.52) | 71.0 | |
Progestogen with 30-40 µg ethinylestradiol: | |||||||
Norethisterone | 27 355 | 8 | 2.24 (1.12 to 4.51) | 2 | 0.73 (0.18 to 2.91) | 80.0 | |
Levonorgestrel phasic | 105 970 | 66 | 3.09 (2.41 to 3.97) | 23 | 1.31 (0.86 to 1.98) | 74.2 | |
Levonorgestrel combined | 104 251 | 57 | 2.92 (2.23 to 3.81) | 21 | 1.30 (0.84 to 2.00) | 73.1 | |
Norgestimate | 267 664 | 119 | 3.52 (2.90 to 4.27) | 46 | 1.44 (1.07 to 1.95) | 72.1 | |
Desogestrel | 170 249 | 168 | 6.61 (5.60 to 7.80) | 33 | 1.43 (1.01 to 2.04) | 83.6 | |
Gestodene | 668 355 | 575 | 6.24 (5.61 to 6.95) | 163 | 1.92 (1.61 to 2.28) | 77.9 | |
Drospirenone | 286 859 | 196 | 6.37 (5.43 to 7.47) | 70 | 2.32 (1.80 to 2.98) | 73.7 | |
Cyproterone | 120 934 | 88 | 6.35 (5.09 to7.93) | 21 | 1.58 (1.02 to 2.44) | 80.7 | |
Progestogen with 20 µg ethinylestradiol: | |||||||
Desogestrel | 470 982 | 246 | 4.81 (4.15 to 5.56) | 76 | 1.52 (1.19 to 1.94) | 76.4 | |
Gestodene | 472 118 | 240 | 5.07 (4.37 to 5.88) | 81 | 1.72 (1.36 to 2.19) | 74.8 | |
Drospirenone | 23 055 | 16 | 6.95 (4.21 to 11.5) | 7 | 2.58 (1.22 to 5.46) | 69.6 | |
Progestogen only: | |||||||
Norethisterone | 44 168 | 6 | 0.68 (0.30 to 1.51) | 3 | 0.41 (0.13 to 1.28) | 66.7 | |
Desogestrel | 29 187 | 3 | 0.61 (0.20 to 1.90) | 3 | 0.63 (0.20 to 1.97) | 50.0 | |
Levonorgestrel releasing intrauterine device | 155 149 | 26 | 0.72 (0.49 to 1.06) | 29 | 0.95 (0.65 to 1.38) | 47.3 |
*Events are venous thromboembolisms.
†Adjusted for age, calendar year, and level of education.