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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Lancet Neurol. 2011 Oct;10(10):922–930. doi: 10.1016/S1474-4422(11)70187-9

Table 1.

Anesthetic agents used in RSE 5, 53, 56

Loading dose Maintenance dose Remarks
Midazolam 0.2 mg/kg 0.2–0.6 mg/kg/h Increasing doses needed with time
Propofol 2 mg/kg 2–5 (−10) mg/kg/h Attention to “PRIS”, especially in young children; combine with BDZ
Barbiturates THP: 1–2 mg/kg
PTB: 5 mg/kg
THP: 1–5 mg/kg/h
PTB: 1–5 mg/kg/h
Loading with repetitive boluses
Long wash-out time

BDZ: benzodiazepines; PRIS: propofol infusion syndrome; PTB: pentobarbital; RSE: refractory status epilepticus; THP: thiopental.