Table 1.
Loading dose | Maintenance dose | Remarks | |
---|---|---|---|
Midazolam | 0.2 mg/kg | 0.2–0.6 mg/kg/h | Increasing doses needed with time |
Propofol | 2 mg/kg | 2–5 (−10) mg/kg/h | Attention to “PRIS”, especially in young children; combine with BDZ |
Barbiturates | THP: 1–2 mg/kg PTB: 5 mg/kg |
THP: 1–5 mg/kg/h PTB: 1–5 mg/kg/h |
Loading with repetitive boluses Long wash-out time |
BDZ: benzodiazepines; PRIS: propofol infusion syndrome; PTB: pentobarbital; RSE: refractory status epilepticus; THP: thiopental.