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. Author manuscript; available in PMC: 2012 Oct 24.
Published in final edited form as: Arch Intern Med. 2011 Jul 25;171(19):1712–1718. doi: 10.1001/archinternmed.2011.351

Table 3.

Discrimination and Reclassification for the Comparison of Models including HbA1c to Classification of Diabetes as a Cardiovascular Risk Equivalent in Diabetic Participants

ATP III RRS
Women’s Health Study
C-statistic for Risk Equivalent 0.515 0.519
C-statistic for model with HbA1c 0.692 0.697
P value for C-statistic comparison <0.001 <0.001
NRI (p value) 26.7% (0.001) 23.6% (0.003)
IDI (p value) 0.072 (<0.001) 0.072 (<0.001)
Reclassification χ2 for Risk Equivalent (p value) 37.6 (<0.001) 35.9 (<0.001)
Reclassification χ2 for model with HbA1c (p value) 14.4 (0.002) 15.9 (0.001)
Physician’s Health Study II
C-statistic for Risk Equivalent 0.563 0.578
C-statistic for model with HbA1c 0.602 0.605
P value for C-statistic comparison 0.015 0.081
NRI (p value) 9.2 % (0.042) 12.4 % (0.005)
IDI (p value) 0.039 (<0.001) 0.041 (<0.001)
Reclassification χ2 for Risk Equivalent (p value) 26.5 (<0.001) 27.1 (<0.001)
Reclassification χ2 for model with HbA1c (p value) 9.8 (0.002) 6.5 (0.011)

ATP III = base covariates from Adult Treatment Panel III, RRS = base covariates from Reynolds risk score